{"id":11887,"date":"2022-01-07T20:12:21","date_gmt":"2022-01-07T20:12:21","guid":{"rendered":"http:\/\/ahelth.com\/the-importance-of-folic-acid-its-sources-and-the-risks-of-deficiency\/"},"modified":"2022-01-08T05:22:08","modified_gmt":"2022-01-08T05:22:08","slug":"the-importance-of-folic-acid-its-sources-and-the-risks-of-deficiency","status":"publish","type":"post","link":"https:\/\/ahelth.com\/tr\/the-importance-of-folic-acid-its-sources-and-the-risks-of-deficiency\/","title":{"rendered":"Folik asidin \u00f6nemi, kaynaklar\u0131 ve eksiklik riskleri"},"content":{"rendered":"

Folik asidin \u00f6nemi, kaynaklar\u0131 ve eksiklik riskleri<\/span><\/span><\/span><\/span><\/p>\n

\n

Folik asidin v\u00fccut i\u00e7in faydalar\u0131<\/span><\/span><\/span><\/span><\/h2>\n

Folik asit, RNA ve DNA \u00fcretimine yard\u0131mc\u0131 olur ve hamilelik, ergenlik ve \u00e7ocukluk gibi h\u0131zl\u0131 b\u00fcy\u00fcme d\u00f6nemlerinde gereklidir. <\/span><\/span><\/span>B12 vitamini taraf\u0131ndan desteklenen folik asit, k\u0131rm\u0131z\u0131 kan h\u00fccresi \u00fcretimini kontrol etmeye yard\u0131mc\u0131 olur ve demirin v\u00fccutta d\u00fczg\u00fcn bir \u015fekilde da\u011f\u0131lmas\u0131na yard\u0131mc\u0131 olur, bu vitaminin eksikli\u011fi kans\u0131zl\u0131\u011fa yol a\u00e7abilir.<\/span><\/span><\/span><\/span><\/p>\n

folik asit kaynaklar\u0131<\/span><\/span><\/span><\/span><\/h2>\n

Folik asit, karaci\u011fer, meyveler, yaprakl\u0131 ye\u015fillikler, maya, bezelye ve kuru fasulye gibi baz\u0131 sebze ve g\u0131dalarda y\u00fcksek konsantrasyonlarda bulunur. <\/span><\/span><\/span>Bir\u00e7ok insan, gerekli miktarda folik asit almak i\u00e7in bu g\u0131dalardan ve sebzelerden yeterince yemez. <\/span><\/span><\/span>Bu da v\u00fccutta bir eksikli\u011fe yol a\u00e7ar. <\/span><\/span><\/span>.<\/span><\/span><\/span><\/span><\/p>\n

\u00c7\u00f6lyak hastal\u0131\u011f\u0131, alkolikler veya irritabl ba\u011f\u0131rsak sendromu olan ki\u015filer, di\u011fer bir\u00e7ok sa\u011fl\u0131k sorununun \u00f6n\u00fcn\u00fc a\u00e7abilecek bir folat eksikli\u011fi geli\u015ftirme riski alt\u0131ndad\u0131r.<\/span><\/span><\/span><\/span><\/p>\n

Hamilelik ve folik asit<\/span><\/span><\/span><\/span><\/h2>\n

Hamilelik s\u0131ras\u0131nda folik asit eksikli\u011fi, fet\u00fcs annenin folik asit kayna\u011f\u0131n\u0131 t\u00fcketti\u011finden hem anne hem de fet\u00fcs i\u00e7in bir risk olu\u015fturur ve bir kad\u0131n\u0131n v\u00fccudunda hamilelikten \u00f6nce yeterli folik asit bulunmas\u0131, beyinde ciddi konjenital malformasyonlar\u0131n \u00f6nlenmesine yard\u0131mc\u0131 olabilir. ve omurga. <\/span>bebek.<\/span><\/span><\/span><\/span><\/p>\n

Bu do\u011fum kusurlar\u0131na n\u00f6ral t\u00fcp kusurlar\u0131 (NTD’ler) denir ve bu kusurun olu\u015fmas\u0131n\u0131 \u00f6nlemek i\u00e7in kad\u0131nlar hamilelikten \u00f6nce bile g\u00fcnl\u00fck folik asit almal\u0131d\u0131r.<\/span><\/span><\/span><\/span><\/p>\n

Kalp ve folik asit<\/span><\/span><\/span><\/span><\/h2>\n

Folik asit ayr\u0131ca kandaki amino asit seviyelerinin kontrol edilmesine de yard\u0131mc\u0131 olur, \u00e7\u00fcnk\u00fc bu asitlerin kandaki y\u00fcksek seviyeleri kalp hastal\u0131\u011f\u0131 gibi \u00e7e\u015fitli hastal\u0131klara yol a\u00e7abilir. <\/span><\/span><\/span>Folik asit de dahil olmak \u00fczere baz\u0131 B vitamini t\u00fcrleri, amino asit seviyelerini d\u00fc\u015f\u00fcrmek i\u00e7in enzimlerle birlikte \u00e7al\u0131\u015f\u0131r. <\/span><\/span><\/span>Koroner arter hastal\u0131\u011f\u0131 ve periferik vask\u00fcler hastal\u0131k gibi hastal\u0131klar bu asidin eksikli\u011fi ile ili\u015fkilendirilmi\u015ftir.<\/span><\/span><\/span><\/span><\/p>\n

Bo\u011faz kanseri \u00f6nleme<\/span><\/span><\/span><\/span><\/h2>\n

T\u0131bbi bir ara\u015ft\u0131rma, folik asidin bo\u011faz kanserine kar\u015f\u0131 koruyabildi\u011fini ve g\u0131rtlakta kan salg\u0131lanmas\u0131n\u0131n, a\u011f\u0131z veya bo\u011faz\u0131n i\u00e7 k\u0131sm\u0131nda kanser h\u00fccreleri i\u00e7erebilen noktalar olarak ortaya \u00e7\u0131kan bir sorun oldu\u011funu bildirdi. <\/span><\/span><\/span>\u0130talyan ara\u015ft\u0131rmac\u0131lar, kansere yol a\u00e7abilecek bo\u011faz problemlerini tedavi etmek i\u00e7in folik asit takviyeleri kullanan bir ara\u015ft\u0131rmadan cesaret verici sonu\u00e7lar ald\u0131klar\u0131n\u0131 s\u00f6ylediler.<\/span><\/span><\/span><\/span><\/p>\n

43 l\u00f6semi hastas\u0131n\u0131n 31’inin alt\u0131 ayl\u0131k folik asit tedavisinden sonra yama boyutunda y\u00fczde 50 k\u00fc\u00e7\u00fclme oldu\u011funu ve her hastan\u0131n sekiz saatte bir be\u015f miligram ald\u0131\u011f\u0131n\u0131 bildirdiler. <\/span><\/span><\/span>Ara\u015ft\u0131rma ekibi, \u00f6nceki \u00e7al\u0131\u015fmalar\u0131n, ba\u015f veya boyun kanseri veya bo\u011fazda l\u00f6semi te\u015fhisi konan hastalar\u0131n kanlar\u0131nda normalden daha d\u00fc\u015f\u00fck folik asit seviyelerine sahip oldu\u011funu g\u00f6sterdi\u011fini kaydetti.<\/span><\/span><\/span><\/span><\/p>\n

Folik asitin t\u0131bbi kullan\u0131m\u0131<\/span><\/span><\/span><\/span><\/h2>\n

Folik asit a\u015fa\u011f\u0131daki durumlar\u0131n tedavisinde kullan\u0131l\u0131r:<\/span><\/span><\/span><\/span><\/p>\n

    \n
  • Do\u011fum kusurlar\u0131n\u0131 \u00f6nleme<\/span><\/span><\/span><\/span><\/li>\n
  • \u00e7\u00f6k\u00fcnt\u00fc, depresyon<\/span><\/span><\/span><\/span><\/li>\n
  • Di\u015f eti iltihab\u0131 (sadece y\u0131kama)<\/span><\/span><\/span><\/span><\/li>\n
  • Y\u00fcksek konsantrasyonda amino asitler (B6 Vitamini ve B12 Vitamini ile birlikte)<\/span><\/span><\/span><\/span><\/li>\n
  • servikal muayene<\/span><\/span><\/span><\/span><\/li>\n
  • Hamilelik ve do\u011fum sonras\u0131 destek<\/span><\/span><\/span><\/span><\/li>\n
  • \u015fizofreni<\/span><\/span><\/span><\/span><\/li>\n<\/ul>\n

    Folik asit eksikli\u011fi<\/span><\/span><\/span><\/span><\/h2>\n

    \u00c7o\u011fu insan yeterli folik asit almaz ve kalp hastal\u0131\u011f\u0131nda y\u00fcksek amino asit seviyeleri yayg\u0131nd\u0131r. <\/span><\/span><\/span>Bat\u0131 \u00fclkelerindeki n\u00fcfusun \u00e7o\u011funda hafif folik asit eksikli\u011fi semptomlar\u0131 vard\u0131r ve folik asit al\u0131m\u0131n\u0131n artt\u0131r\u0131lmas\u0131yla y\u0131lda 13.500 kardiyovask\u00fcler hastal\u0131k \u00f6l\u00fcm\u00fcn\u00fcn kurtar\u0131lmas\u0131 m\u00fcmk\u00fcnd\u00fcr.<\/span><\/span><\/span><\/span><\/p>\n

    Folik asit, h\u00fccre yap\u0131m\u0131nda \u00f6nemli bir rol oynar ve bu asit eksikli\u011finin komplikasyonlar\u0131ndan biri, megaloblastik anemi olarak bilinen bir t\u00fcr aneminin nedenidir. <\/span><\/span><\/span>\u00c7o\u011fu durumda, do\u011fum kontrol hap\u0131 alan, emilim bozuklu\u011fu olan, karaci\u011fer hastal\u0131\u011f\u0131 olan veya alkolik olan ki\u015filerde folik asit eksikli\u011fi vard\u0131r.<\/span><\/span><\/span><\/span><\/p>\n

    Bu eksiklik genellikle i\u015fitme kayb\u0131 olan ya\u015fl\u0131 ki\u015filerde g\u00f6r\u00fcl\u00fcr. <\/span><\/span><\/span>Antasitler, triamteren, antikonv\u00fclzanlar, simetidin, kanser ila\u00e7lar\u0131 gibi baz\u0131 ila\u00e7lar folik asidin etkisini zay\u0131flatabilir.<\/span><\/span><\/span><\/span><\/p>\n

    Gerekli folik asit dozu<\/span><\/span><\/span><\/span><\/h2>\n

    Hamile olan veya hamile kalmay\u0131 planlayan kad\u0131nlar do\u011fum kusurlar\u0131 riskini azaltmak i\u00e7in g\u00fcnde 400 ml folik asit almal\u0131d\u0131r ve doktorlar bazen kalp hastal\u0131\u011f\u0131 riskini azaltmak i\u00e7in bu dozu \u00f6nermektedir.<\/span><\/span><\/span><\/span><\/p>\n

    G\u0131da ve \u0130la\u00e7 Dairesi (FDA), haplar\u0131n folik asit ile desteklenmesini \u015fart ko\u015fuyor. <\/span><\/span><\/span>D\u00fczenli olarak tah\u0131l yiyenlerin g\u00fcnde sadece 100 ml folik aside ihtiyac\u0131 vard\u0131r. <\/span><\/span><\/span>Bununla birlikte, bu d\u00fc\u015f\u00fck seviye genellikle v\u00fccutta y\u00fcksek seviyelerde folik asit tutmaz. <\/span><\/span><\/span>Bu asidin eksikli\u011fini \u00f6nlemek i\u00e7in hamile bir kad\u0131n g\u00fcnde 300-400 ml t\u00fcketmelidir.<\/span><\/span><\/span><\/span><\/p>\n

    Folik asit eksikli\u011fi ve Down sendromu<\/span><\/span><\/span><\/span><\/h2>\n

    Down sendromlu \u00e7ocuklar\u0131n anneleri \u00fczerinde genetik m\u00fchendisli\u011fi kullan\u0131larak M\u0131s\u0131r’da t\u00fcr\u00fcn\u00fcn ilk \u00f6rne\u011fi olan bir ara\u015ft\u0131rma, hamile annede baklagillerde bulunan folik asitten zengin g\u0131dalar\u0131n eksikli\u011finin, anne s\u00fct\u00fcnde art\u0131\u015fa yol a\u00e7t\u0131\u011f\u0131n\u0131 buldu. kromozom kusurlar\u0131n\u0131n say\u0131s\u0131. <\/span>Bu, Down \u00e7ocuk sahibi olma olas\u0131l\u0131\u011f\u0131n\u0131 art\u0131r\u0131r.<\/span><\/span><\/span><\/span><\/p>\n

    Ara\u015ft\u0131rma, anne kan\u0131ndan al\u0131nan DNA’da belirli bir gende mutasyon olmad\u0131\u011f\u0131n\u0131 ve bu mutasyonun annelerde Down \u00e7ocuk oran\u0131n\u0131n artmas\u0131nda \u00f6nemli bir fakt\u00f6r olmad\u0131\u011f\u0131n\u0131 kan\u0131tlad\u0131, ancak \u00f6nemli olan \u00e7al\u0131\u015fma \u015fuydu: Annelerin t\u00fcketti\u011fi folik asit miktar\u0131, kontrol \u00f6rne\u011fi ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda ve bir kad\u0131n do\u011fum uzman\u0131 ve jinekolog taraf\u0131ndan yak\u0131n takipte yaprakl\u0131 sebzeler, baklagiller ve folik asit t\u00fcketimine y\u00f6nelik gerekli miktardan istatistiksel olarak daha azd\u0131.<\/span><\/span><\/span><\/span><\/p>\n

    sorular ve cevaplar<\/span><\/span><\/span><\/span><\/h2>\n

    Folik asit nedir?<\/span><\/span><\/span><\/span><\/h3>\n

    B vitamininin bir\u00e7ok t\u00fcr\u00fcnden biridir ve hamileli\u011fin ilk g\u00fcnlerinde organlar olu\u015ftu\u011funda fet\u00fcs\u00fcn b\u00f6l\u00fcnmesi ve \u00fcremesi i\u00e7in \u00f6nemli ve \u00e7ok gerekli bir vitamin olan B9 olarak adland\u0131r\u0131l\u0131r. merkezi sinir sisteminin h\u00fccreleri. <\/span><\/span><\/span>\u00c7o\u011fu g\u0131dada, \u00f6zellikle sebze, meyve, tah\u0131l \u00fcr\u00fcnleri, et, mercimek, fasulye ve f\u0131nd\u0131kta bulunur. <\/span><\/span><\/span>Suda \u00e7\u00f6z\u00fcnen bir vitamin oldu\u011fu i\u00e7in fazlas\u0131 idrarla at\u0131l\u0131r ve bu nedenle g\u00fcvenli bir vitamindir.<\/span><\/span><\/span><\/span><\/p>\n

    Bu asit konjenital malformasyonlara kar\u015f\u0131 koruma sa\u011fl\u0131yor mu?<\/span><\/span><\/span><\/span><\/h3>\n

    Hamilelikten \u00f6nce folik asit alan bir kad\u0131n\u0131n, fet\u00fcs\u00fcnde spinal kord malformasyonlar\u0131 (spina bifida ve anensefali gibi) geli\u015ftirme riskini %50-75 oran\u0131nda azaltt\u0131\u011f\u0131 ampirik ve kesin olarak ve birden fazla t\u0131bbi ara\u015ft\u0131rmada g\u00f6sterilmi\u015ftir.<\/span><\/span><\/span><\/span><\/p>\n

    Folik asit zararl\u0131 m\u0131?<\/span><\/span><\/span><\/span><\/h3>\n

    Herhangi bir zarar\u0131 olmaz ancak B2 vitamini eksikli\u011fi ya\u015fayanlar\u0131n gere\u011finden fazla almamas\u0131 \u00f6nerilir.<\/span><\/span><\/span><\/span><\/p>\n

    Folik asit ne zaman al\u0131n\u0131r?<\/span><\/span><\/span><\/span><\/h3>\n

    Hamilelikten \u00f6nce, hamileli\u011fin ilk ay\u0131n\u0131n sonuna kadar g\u00fcnde en az bir ay ve tercihen hamileli\u011fin \u00fc\u00e7\u00fcnc\u00fc ay\u0131n\u0131n sonuna kadar \u00f6nlem olarak al\u0131n\u0131r. <\/span><\/span><\/span>%50’ye varan plans\u0131z gebelikler olabilece\u011finden, R\u0130A ve hap gibi daha etkili do\u011fum kontrol y\u00f6ntemlerini kullanmay\u0131 b\u0131rak\u0131r b\u0131rakmaz gebeli\u011fin al\u0131nmas\u0131 \u00f6nerilir.<\/span><\/span><\/span><\/span><\/p>\n

    Folik asidin ba\u015fka faydalar\u0131 var m\u0131?<\/span><\/span><\/span><\/span><\/h3>\n

    Evet, folik asit, kalp, b\u00f6brek, dudak ve yar\u0131k damak gibi di\u011fer organlardaki fet\u00fcste konjenital malformasyonlar\u0131n g\u00f6r\u00fclme s\u0131kl\u0131\u011f\u0131n\u0131 azaltabilir ve ayr\u0131ca k\u0131rm\u0131z\u0131 kan h\u00fccrelerinin \u00fcretiminde ve hemoglobin art\u0131\u015f\u0131nda \u00e7ok \u00f6nemli bir rol oynar.<\/span><\/span><\/span><\/span><\/p>\n

    Son y\u0131llarda, folik asidin koroner arter hastal\u0131\u011f\u0131n\u0131 ve fel\u00e7leri \u00f6nlemeye yard\u0131mc\u0131 olabilece\u011fini g\u00f6steren t\u0131bbi \u00e7al\u0131\u015fmalar yap\u0131lm\u0131\u015ft\u0131r. <\/span><\/span><\/span>Kolon ve rahim a\u011fz\u0131 kanseri gibi baz\u0131 kanser t\u00fcrlerine kar\u015f\u0131 koruma sa\u011flad\u0131\u011f\u0131na dair baz\u0131 kan\u0131tlar vard\u0131r.<\/span><\/span><\/span><\/span><\/p>\n<\/div>\n

    .<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

    Folik asidin \u00f6nemi, kaynaklar\u0131 ve eksiklik riskleri Ne oldu\u011funu merak ediyor musun? Folik asit? V\u00fccut taraf\u0131ndan k\u0131rm\u0131z\u0131 kan h\u00fccreleri \u00fcretmek i\u00e7in kullan\u0131lan folik asit veya folik asit olarak bilinen B vitamini 9 numaral\u0131 vitamin bile\u015fi\u011fi midir, bu kompleks vitaminler proteinlerin ve ya\u011flar\u0131n uygun metabolizma s\u00fcreci i\u00e7in gereklidir ve sindirim sistemini, cildi, sa\u00e7\u0131 korumaya yard\u0131mc\u0131 olur. …<\/p>\n","protected":false},"author":1,"featured_media":11001,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[],"class_list":["post-11887","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-tr"],"yoast_head":"\nFolik asidin \u00f6nemi, kaynaklar\u0131 ve eksiklik riskleri - the health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ahelth.com\/tr\/the-importance-of-folic-acid-its-sources-and-the-risks-of-deficiency\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Folik asidin \u00f6nemi, kaynaklar\u0131 ve eksiklik riskleri - the health\" \/>\n<meta property=\"og:description\" content=\"Folik asidin \u00f6nemi, kaynaklar\u0131 ve eksiklik riskleri Ne oldu\u011funu merak ediyor musun? 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